References
[1] . Chacko, M., Sarma, P. S., Harikrishnan, S., Zachariah, G., & Jeemon, P. (2020). Family history of cardiovascular disease and risk of premature coronary heart disease: A matched case-control study. Wellcome Open Research, 5(5), 70. https://doi.org/10.12688/wellcomeopenres.15829.2
[2] . CDC. (2024, January 17). Social Determinants of Health (SDOH). CDC. https://www.cdc.gov/about/priorities/why-is-addressing-sdoh-important.html
[3] . Choi, S. W., Mak, T. S.-H., & O’Reilly, P. F. (2020). Tutorial: a guide to performing polygenic risk score analyses. Nature Protocols, 15(9), 2759–2772. https://doi.org/10.1038/s41596-020-0353-1
[4] . Gene and Environment Interaction. (2018). National Institute of Environmental Health Sciences. https://www.niehs.nih.gov/health/topics/science/gene-env#:~:text=Introduction
[5] . Hernandez, L. M. (2016). Genetics and Health. Nih.gov; National Academies Press (US). https://www.ncbi.nlm.nih.gov/books/NBK19932
[6] . Krisela Steyn, & Albertino Damasceno. (2009). Lifestyle and Related Risk Factors for Chronic Diseases. Nih.gov; The International Bank for Reconstruction and Development / The World Bank. https://www.ncbi.nlm.nih.gov/books/NBK2290/
[7] . Lewis, C. M., & Vassos, E. (2020). Polygenic risk scores: from research tools to clinical instruments. Genome Medicine, 12(1). https://doi.org/10.1186/s13073-020-00742-5
[8] . Mostafavi, H., Harpak, A., Agarwal, I., Conley, D., Pritchard, J. K., & Przeworski, M. (2020). Variable prediction accuracy of polygenic scores within an ancestry group. ELife, 9. https://doi.org/10.7554/elife.48376
[9] . Norori, N., Hu, Q., Aellen, F. M., Faraci, F. D., & Tzovara, A. (2021). Addressing bias in big data and AI for health care: A call for open science. Patterns, 2(10), 100347. https://doi.org/10.1016/j.patter.2021.100347
[10] . National Human Genome Research Institute. (2020, August 11). Polygenic Risk Scores. Genome.gov. https://www.genome.gov/Health/Genomics-and-Medicine/Polygenic-risk-scores
[11] . Polygenic Risk Score (PRS). (n.d.). Genome.gov. https://www.genome.gov/genetics-glossary/Polygenic-Risk-Score
[12] . Polygenic Risk Scores in Complex Disease Research. (2020). Illumina.com. https://www.illumina.com/areas-of-interest/complex-disease-genomics/polygenic-risk-scores.html#:~:text=Polygenic%20risk%20scores%20
[13] . Social determinants of health. (n.d.). Www.who.int.
[14] . https://www.who.int/health-topics/social-determinants-of-health#tab=tab_
[15] . Uffelmann, E., Huang, Q. Q., Munung, N. S., de Vries, J., Okada, Y., Martin, A. R., Martin, H. C., Lappalainen, T., & Posthuma, D. (2021). Genome-wide association studies. Nature Reviews Methods Primers, 1(1). https://doi.org/10.1038/s43586-021-00056-9
[16] . Volk, H. E., Kerin, T., Lurmann, F., Hertz-Picciotto, I., McConnell, R., & Campbell, D. B. (2014). Autism Spectrum Disorder. Epidemiology, 25(1), 44–47. https://doi.org/10.1097/ede.0000000000000030
[17] . What are complex or multifactorial disorders?: MedlinePlus Genetics. (2021).
[18] . Medlineplus.gov. https://medlineplus.gov/genetics/understanding/mutationsanddisorders/complexdisord ers/#:~:text=Common%20health%20 problems%20such%20as
[19] . WHO. (2024). Social Determinants of Health. World Health Organization. https://www.who.int/health-topics/social-determinants-of-health#tab=tab_1